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KMID : 1144220200260020143
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Journal of Menopausal Medicine
2020 Volume.26 No. 2 p.143 ~ p.146
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Two Cases of Primary Ovarian Insufficiency Accompanied by High Serum Anti-Mullerian Hormone Levels and Preservation of Ovarian Follicles
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Chun Sung-Wook
Koo Yun-Hee
Na Yong-Jin
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Abstract
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Primary ovarian insufficiency (POI) is defined as the presence of amenorrhea for ≥ 4 months accompanied by evidence of two serum follicle-stimulating hormone levels in the menopausal range in women aged < 40 years. Anti-Mullerian hormone (AMH) has been recognized as the most reliable marker of ovarian reserve status, and its serum level is very low or undetectable in women with POI. Here we report two cases of patients who were diagnosed with POI despite high serum AMH levels and preservation of ovarian follicles, as revealed by ultrasound. In addition, we have presented a review of the current literature regarding this condition.
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KEYWORD
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Anti-Mullerian hormone, Ovarian follicle, Primary ovarian insufficiency
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